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Fall 2008 Newsletter
In this issue
Markush structure storage & search IUPAC Name to Structure Generation Instant JChem; Cartridge & server support New: JChem for Excel Events & dates for your diary Goodies Housekeeping: New license file system
Latest release features
Storing & searching Markush structures without enumeration

Following on from the release of the Markush Enumeration Calculator Plugin, we extend Markush support with structure storage and search in JChem Base and Instant JChem (Cartridge support soon).
As an ongoing project we are continually adding new features such as position variation (see image), R-groups (with any nesting), link nodes, atom and bond lists and repeating units in the drawing package, MarvinSketch, so with this release we enable storage and search of these features from within the JChem database tools, all without enumerating the structure.
For working with search results we also introduce a novel structure reduction method to minimise the total number of hits and focus on diverse results.
Find out more. Download JChem.

Import chemical names into Marvin & JChem

Supporting both traditional and preferred IUPAC names as input, users can generate corresponding chemical structures.
Within MarvinSketch you can paste structure names directly into the canvas and see the resulting structure and within JChem, batch processing of name files can be used to populate chemical database tables. In addition to the GUI and API access we are working on web based deployments to chemicalize the web (visit www.chemicalize.org).
Find out more. Structure to Name. Download Marvin.

Future feature focus
Instant JChem Cartridge support & middle tier still this year

Instant JChem is already powerful for handling databases on the desktop but for larger organizations and those integrating multiple ways to share data, enterprise integration is essential.
The next release of Instant JChem (v2.4) will include support for ChemAxon's Oracle® Cartridge and with the subsequent release (v 3.0) we will introduce Instant JChem server. The server will provide a 3-tier architecture, allowing consolidation of much of the processing onto the server tier, freeing up the client from these data intensive operations. The server will be HTTP based and future extensions will allow web applications and web services to be built around this architecture. Instant JChem v2.4 is expected in October and v3.0 by the end of the year.
Find out more. Track the next release; topic at our forum.

New Product
JChem for Excel (expected release October 2008)

JChem for Excel enables chemical structures within MicroSoft Excel® spread-sheets. Users can open and share .xls files containing chemical structures, connect with shared JChem Base and JChem Cartridge database platforms, add and edit structures, import and export popular chemical file formats, browse, sort, filter and search spreadsheet chemical data using the familiar Excel controls. Using pre-loaded and custom Excel functions, which work with ChemAxon's Calculator Plugin technology, rows can be automatically populated with structure based predictions and combined prediction arguments. Users can also easily populate rows with R-group decomposition products. To be notified of launch please send us an email

Events & dates for the diary
US UGM archive opens

Over 60 participants enjoyed Boston and ChemAxon's inaugural US UGM. Visit US UGM archive (includes presentations). Visit meeting report by Yvonne Martin. Visit all UGM archives

Upcoming conferences and meetings

I'm attending, let's meet

ChemAxon Training and User Group Meetings: 2009

Track future User Meetings; topic at our forum

Goodies
Developers: Marvin Applet JavaScript + Chemical Terms new code examples

This code example shows the JavaScript support now in Marvin and allows interactions with Chemical Terms calculations on the client side in real time during structure editing. Visit code example. Visit all Marvin code examples.

New product beta testers required: Metabolizer

We are developing a metabolite prediction application called Metabolizer. Metabolizer can be used with biotransformation libraries to generate the all or major metabolites of given substrates as well as predicting metabolic stability, even in batch mode.
We are in the final stages of GUI development and need user feedback to shape the final application, do you want to participate in beta testing? Yes please.

Housekeeping
New license file system changeover: October 1st

We have introduced a new licensing system with Marvin/JChem 5.0 and newer. Users running these versions should already have moved to the new file based license before support stops for the old license key system (October 1st, 2008). To find out more about this please see these links: Commercial users, free Academic Package users. If you need further support please contact us.