Overview

Compounds having ionizable groups exist in solution as a mixture of different ionic forms. The ionization of those groups and so the ratio of the ionic forms depends on the pH. Since logP describes the hydrophobicity of one form only, the apparent logP value can be different. The octanol-water distribution coefficient, logD represents the compounds at any pH value.

Learn more about how the plugin calculates logD.

This project was partially funded by the Hungarian National Office for Research and Technology under the contract number OMFB-00007/2006.