Author: György Pirok

Plexus Analysis

May 25, 2016 - Presentation
Plexus Analysis is a web-based data visualization and analytics software for all industries. It can receive data from Plexus Connect tables, from files and through its web service interfa…

Making “Real” Molecules in Virtual Space

Jan 13, 2006 - Publication
Predicting “realistic” compounds of given chemical reactions with virtual synthesis tools usually requires the manual intervention of experienced chemists in the enumeration p…
chemicalterms

Chemical Terms - Functions for Cheminformatics

Jun 5, 2008 - Poster
Pharmaceutical research is not just about molecules, it is about realizable molecules having certain properties. The available set of computable properties is growing, each function usual…
chemicalterms

Chemical Terms - Functions for Cheminformatics

Aug 8, 2008 - Poster
Pharmaceutical research is not just about molecules, it is about realizable molecules having certain properties. The available set of computable properties is growing, each function usual…
libdesign in Plexus

Design of synthetically accessible virtual libraries with Plexus

Jul 10, 2014 - Presentation
Virtual enumeration of chemical reactions as part of virtual library design plays a pivotal role in designing potential drug molecules and generating new ideas. Reactor is the reaction en…
donor

Virtual Screening Using Fingerprints Part I. A Hybrid Approach to Pharmacophore Point Perception

Aug 15, 2003 - Poster
About 90% of drug targets cannot be crystallized. If the 3D structure of the active site is not available, a pharmacophore model is created. Such models are typically based on compounds t…
gyorgy pirok

Majors and Minors

Sep 25, 2013 - Presentation
The Metabolizer software tool of ChemAxon predicts and ranks the metabolites of drugs and other xenobiotics. The knowledge base is stored in the form of biotransformation libraries which …
Product: Metabolizer
virtualsynthesis

Virtual synthesis with “smart” reactions

Nov 15, 2003 - Poster
Modeling chemical structures is a scientifically well grounded area, proving it’s self in theory as well as in practice. However, there are many traps on the road to virtual reaction pr…
novel

A Novel Approach to Modeling Molecular Transformations and its Various Applications

Aug 15, 2003 - Poster
With the advent of high throughput screening and combinatorial chemistry computer assisted chemistry plays an important role in selecting and designing new drug candidates. Pharmaceutical…
metabolizer

Prediction of Xenobiotic Metabolism

May 29, 2013 - Presentation
Metabolizer is a new tool from ChemAxon to predict and rank the metabolites of drugs and xenobiotics. Metabolizer contains a built-in library of human biotransformation schemes which were…
Product: Metabolizer
reactor

How can generic reactions be specific? Virtual synthesis with “smart” reactions.

Apr 1, 2004 - Poster
High throughput screening initiated a new gold-rush in drug discovery. Although the reef of combinatorial chemistry has enriched the pharmaceutical industry with many new biologically act…
standard

Standardizer - Molecular Cosmetics for Chemoinformatics

Jun 14, 2007 - Poster
A chemical compound can appear in various forms and its graphical representation often depends on the taste of the chemist. These variants are usually represented with different graphs in…
checker

Restoration of Molecular Artifacts: The new structure checker framework of Standardizer

May 20, 2010 - Presentation
Chemical structures sometimes contain various drawing errors and those originated from old databases often suffer from the limitations of the early technologies. Having no functions to ha…
pirok

Virtual synthesis and metabolism - new development

Sep 15, 2009 - Presentation
ChemAxon’s Reactor technology has recently been integrated in the Instant JChem platform providing an easy to use interface for Combichem library generation in databases. A new appl…
Products: Reactor, Metabolizer
gyorgy

Metabolizer and humans: this time it's personal

Sep 26, 2012 - Presentation
Metabolizer is a new product predicting the metabolites of drugs and other xenobiotics. Major metabolite prediction will be demonstrated with the help of the embedded human biotransformat…
Product: Metabolizer
dubnium

Standardizer - Molecular Cosmetics for Chemoinformatics

Jul 15, 2006 - Poster
A chemical compound can appear in various forms and its graphical representation often depends on the taste of the chemist. These variants are usually represented with different graphs in…
virtreactor

Virtual reaction design for chemists

Sep 14, 2010 - Presentation
Library enumeration is a powerful way for the generation libraries containing loads of NON-synthesizable compounds. At least not on that planned synthetic route due to activation/deactiva…
Product: Reactor
oracle

JChem Cartridge: Cheminformatics Platform for Oracle

Jun 14, 2007 - Poster
JChem Cartridge adds chemical knowledge to the Oracle platform. Data can be searched by structure, substructure and similarity criteria through extending Oracle’s native SQL languag…
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