Institution: Eli Lilly and Co.

lilly

SPrime: Computational Chemistry Application and Framework for Drug Discovery

Sep 15, 2009 - Presentation
We have designed SPrime (System for Predictive In-silico Method) – a new computational chemistry application and framework for drug discovery. It enables scientists to design librar…
daniel robertson

The Lilly Open Innovation Drug Discovery Program (OIDD)

Sep 24, 2013 - Presentation
Through OIDD, Lilly has established a network of top global research talent at academic and biotech institutions to provide them access to proprietary, in vitro phenotypic and target-base…
D2_11_James_A_Lumley

Making Workflows Work: Enterprise deployment of KNIME at Lilly

May 21, 2014 - Presentation
Workflow tools claim an easy approach to automate tasks and provide interoperability between software packages. The metaprogramming concept of graphical workflows should create a lower b…
Product group: Workflow tools
daniel rob

The Lilly Open Innovation Drug Discovery Program

Sep 26, 2012 - Presentation
Through the Open Innovation Drug Discovery program (OIDD), Lilly has established a network of top global research talent at academic and biotech institutions to provide them access to pro…
lilly

A knowledge-based approach for reaction generation: development, validation and applications

Jun 4, 2009 - Presentation
We present a new method for knowledge-based driven reaction generation. The structural changes at the reaction centre are described using reaction vectors1. The reaction vectors are deriv…
eliplexus

Open Innovation Drug Discovery Program

Sep 9, 2013 - Poster
Plexus is a brand-new chemistry application by ChemAxon which provides simple, yet powerful workflows for handling chemical structure processes commonly used by discovery chemists. The ap…

Kinase Inhibitor Data Modeling and de Novo Inhibitor Design with Fragment Approaches

Sep 30, 2009 - Publication
A reconstructive approach based on computational fragmentation of existing inhibitors and validated kinase potency models to recombine and create “de novo” kinase inhibitor small mole…

A simple and efficient approach to reversed-phase HPLC method screening

Jan 1, 2009 - Publication
The development and utility of an efficient HPLC method screening strategy using only four columns for the separation of pharmaceutical compounds and related impurities is presented. The …

The Lilly Open Innovation Drug Discovery Program (OIDD)

May 28, 2013 - Presentation
Through OIDD, Lilly has established a network of top global research talent at academic and biotech institutions to provide them access to proprietary, in vitro phenotypic and target-base…

3D QSAR Methods: Phase and Catalyst Compared

May 4, 2007 - Publication
The programs Phase and Catalyst HypoGen are compared for their performance in determining three-dimensional quantitative structure-activity relationships. Eight sets of compounds with mea…