Institution: Eli Lilly and Co.
The Lilly Open Innovation Drug Discovery Program
Sep 26, 2012 - PresentationThrough the Open Innovation Drug Discovery program (OIDD), Lilly has established a network of top global research talent at academic and biotech institutions to provide them access to pro…
Making Workflows Work: Enterprise deployment of KNIME at Lilly
May 21, 2014 - PresentationWorkflow tools claim an easy approach to automate tasks and provide interoperability between software packages. The metaprogramming concept of graphical workflows should create a lower b…
SPrime: Computational Chemistry Application and Framework for Drug Discovery
Sep 15, 2009 - PresentationWe have designed SPrime (System for Predictive In-silico Method) – a new computational chemistry application and framework for drug discovery. It enables scientists to design librar…
The Lilly Open Innovation Drug Discovery Program (OIDD)
Sep 24, 2013 - PresentationThrough OIDD, Lilly has established a network of top global research talent at academic and biotech institutions to provide them access to proprietary, in vitro phenotypic and target-base…
A knowledge-based approach for reaction generation: development, validation and applications
Jun 4, 2009 - PresentationWe present a new method for knowledge-based driven reaction generation. The structural changes at the reaction centre are described using reaction vectors1. The reaction vectors are deriv…
Open Innovation Drug Discovery Program
Sep 9, 2013 - PosterPlexus is a brand-new chemistry application by ChemAxon which provides simple, yet powerful workflows for handling chemical structure processes commonly used by discovery chemists. The ap…
Kinase Inhibitor Data Modeling and de Novo Inhibitor Design with Fragment Approaches
Sep 30, 2009 - PublicationA reconstructive approach based on computational fragmentation of existing inhibitors and validated kinase potency models to recombine and create “de novo” kinase inhibitor small mole…
A simple and efficient approach to reversed-phase HPLC method screening
Jan 1, 2009 - PublicationThe development and utility of an efficient HPLC method screening strategy using only four columns for the separation of pharmaceutical compounds and related impurities is presented. The …
The Lilly Open Innovation Drug Discovery Program (OIDD)
May 28, 2013 - PresentationThrough OIDD, Lilly has established a network of top global research talent at academic and biotech institutions to provide them access to proprietary, in vitro phenotypic and target-base…
Distributed Drug Discovery, Part 3: Using D3 Methodology to Synthesize Analogs of an Anti-Melanoma Compound
Dec 23, 2008 - PublicationFor the successful implementation of Distributed Drug Discovery (D3) (outlined in the accompanying Perspective), students, in the course of their educational laboratories, must be able to…
3D QSAR Methods: Phase and Catalyst Compared
May 4, 2007 - PublicationThe programs Phase and Catalyst HypoGen are compared for their performance in determining three-dimensional quantitative structure-activity relationships. Eight sets of compounds with mea…