Institution: F. Hoffmann-La Roche AG


SAR Analyzer - intuitive access to SAR information

May 18, 2011 - Presentation
In an endeavor to create an interactive SAR analysis platform at Roche, we aim at providing a portfolio of data analysis techniques that facilitate the navigation of complex data landscap…

Analyzing search hits with ChemAxon's Markush Enumeration tool

May 17, 2011 - Presentation
A novelty search is a time consuming task. A patent search and analysis using a classical Markush database is compared to ChemAxon’s Markush Enumeration Tool performing the same tas…

Intuitive Structure-Activity Analysis for Medicinal Chemists

May 22, 2012 - Poster
For a medicinal chemist, the association between chemical structure information and multiple property and assay data is vital. However, identification of structure-activity relationship (…

Intuitive Patent Markush Structure Visualization Tool for Medicinal Chemists

Mar 7, 2011 - Publication
A Markush, or generic structure, is a widely used convention in chemical and pharmaceutical patents. The flexibility and complexity of this format, however, preclude an easy understanding…