Federal University of Goiás « Institution « ChemAxon – Software for Chemistry and Biology

Institution: Federal University of Goiás

Tuning hERG Out: Antitarget QSAR Models for Drug Development

Feb 11, 2014 - Publication

Several non-cardiovascular drugs have been withdrawn from the market due to their inhibition of hERG K+ channels that can potentially lead to severe heart arrhythmia and death. As hERG sa…

Authors: Rodolpho C. Braga, Vinícius Alves, Meryck Silva, Eugene Muratov, Dennis Fourches, Alexander Tropsha, Carolina H. Andrade (Federal University of Goiás, University of North Carolina at Chapel Hill)

Product group: Discovery toolkit