Institution: Vertex Pharmaceuticals

Marvin Live at Vertex Pharmaceuticals Incorporated

Sep 14, 2016 - Presentation
We will describe briefly how Marvin Live is used at Vertex Pharmaceuticals Incorporated. We will share our involvement in the early development of Marvin Live.

ASAP - Emphasizing Multidimensional Drug Discovery

Sep 16, 2009 - Presentation
One of the biggest challenges facing drug discovery teams is extracting information from the large volume of data generated in the course of a lead optimization effort, and using this inf…

An Integrated Approach to Library Design

Jun 13, 2007 - Presentation
A chemist designing a combinatorial library must consider many criteria when selecting reagents for synthesis. Factors such as target potency, physical properties, metabolic stability, an…

VERDI - An Extensible Cheminformatics System

Jun 14, 2007 - Presentation
As part of an informatics infrastructure which unites chemical and biological information, we have created VERDI – The Vertex Research Database Interface. VERDI is a cheminformatics…

An Analysis of the Binding Efficiencies of Drugs and Their Leads in Successful Drug Discovery Programs

Mar 17, 2010 - Publication
In order to investigate the evolution of binding efficiency in successful drug discovery programs, a data set of 60 lead/drug pairs with known binding affinities has been compiled and ana…