Institution: Vertex Pharmaceuticals

Marvin Live at Vertex Pharmaceuticals Incorporated

Sep 14, 2016 - Presentation
We will describe briefly how Marvin Live is used at Vertex Pharmaceuticals Incorporated. We will share our involvement in the early development of Marvin Live.

ASAP - Emphasizing Multidimensional Drug Discovery

Sep 16, 2009 - Presentation
One of the biggest challenges facing drug discovery teams is extracting information from the large volume of data generated in the course of a lead optimization effort, and using this inf…

VERDI - An Extensible Cheminformatics System

Jun 14, 2007 - Presentation
As part of an informatics infrastructure which unites chemical and biological information, we have created VERDI – The Vertex Research Database Interface. VERDI is a cheminformatics…

An Integrated Approach to Library Design

Jun 13, 2007 - Presentation
A chemist designing a combinatorial library must consider many criteria when selecting reagents for synthesis. Factors such as target potency, physical properties, metabolic stability, an…

An Analysis of the Binding Efficiencies of Drugs and Their Leads in Successful Drug Discovery Programs

Mar 17, 2010 - Publication
In order to investigate the evolution of binding efficiency in successful drug discovery programs, a data set of 60 lead/drug pairs with known binding affinities has been compiled and ana…